Development and implementation of a database system to manage a large-scale mouse ENU-mutagenesis program.

doi:10.1007/s00335-004-2265-8

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Development and implementation of a database system to manage a large-scale mouse ENU-mutagenesis program.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 2004

Masuya Hiroshi, Nakai Yuji, Motegi Hiromi, Niinaya Norio, Kida Yuichiro, Kaneko Yoshiharu, Aritake Haruhiko, Suzuki Nobuaki, Ishii Jun, Koorikawa Koji, Suzuki Tomohiro, Inoue Maki, Kobayashi Kimio, Toki Hideaki, Wada Yumiko, Kaneda Hideki, Ishijima Junko, Takahashi K Ryo, Minowa Osamu, Noda Tetsuo, Wakana Shigeharu, Gondo Yoichi, Shiroishi Toshihiko

Abstract excerpt

A mouse ENU-mutagenesis program at RIKEN GSC has been initiated to conduct a large-scale, genome-wide, early- and late-onset phenotypic screen of mutant mice. We screened about a hundred mice every week with a comprehensive set of phenotype assays including behavioral tests based on a modified SHIRPA protocol, blood tests (both clinical biochemical testing and hemogram), and measurement of locomotor activity in...

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PMID: 15170230
DOI: 10.1007/s00335-004-2265-8

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