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Article

Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B.

Journal of cell science - 15 Nov 2005

Bompard Guillaume, Sharp Stewart J, Freiss Gilles, Machesky Laura M

Abstract excerpt

Numerous scaffold proteins coordinate signals from the environment with actin-based protrusions during shape change and migration. Many scaffolds integrate signals from Rho-family GTPases to effect the assembly of specific actin structures. Here we investigate the mechanism of action MIM-B (missing in metastasis-B) on the actin cytoskeleton. MIM-B binds actin monomer through a WASP homology 2 motif, bundles actin...

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Identifiers

PMID: 16280553
DOI: 10.1242/jcs.02640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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