Article
MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorption.
The Journal of biological chemistry - 13 Jan 2006
Kim Michael S, Day Chris J, Selinger Christina I, Magno Carly L, Stephens Sebastién R J, Morrison Nigel A
Abstract excerpt
MCP-1 (monocyte chemotactic protein-1) is a CC chemokine that is induced by receptor activator of NFkappaB ligand (RANKL) in human osteoclasts. In the absence of RANKL, treatment of human peripheral blood mononuclear cells with macrophage colony-stimulating factor and MCP-1 resulted in tartrate-r...
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