Article
[Generation of dendrite cells and the use of immunomodulators of bacterial origin as cell differentiation inducers].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Akhmatova N K, Lebedinskaia O V, Kiselevskiĭ M V, Makashin A I, Semenova I B, Semenov B F
Abstract excerpt
The generation of ripe dendrite cells (DC) of marrow origin was obtained with the use of the vaccine Immunovac-BN-4, an immunomodulator of microbial origin, as well as Klebsiella pneumoniae LPS and TNF-alpha, as ripening inducers. These inducers equally led to the ripening of DC. The generation of ripe DC was characterized by morphological, phenotypical and functional changes. The immunophenotype of cells altered...
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