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Article

The 103I variant of the melanocortin 4 receptor is associated with low serum triglyceride levels.

The Journal of clinical endocrinology and metabolism - 1 Feb 2006

Brönner Günter, Sattler Alexander M, Hinney Anke, Soufi Muhidien, Geller Frank, Schäfer Helmut, Maisch Bernhard, Hebebrand Johannes, Schaefer Juergen R

Abstract excerpt

CONTEXT: The melanocortin 4 receptor (MC4R) is an essential regulator of energy intake and body weight. Recently, the V103I polymorphism of MC4R has been shown to be negatively associated with body mass index. This suggests that serum lipids and blood pressure in individuals carrying the 103I allele might be influenced as well. OBJECTIVE: The objective of this study was to determine whether the most common...

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Share to Receptor, Melanocortin, Type 4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 16278267
DOI: 10.1210/jc.2005-0919

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The 103I variant of the melanocortin 4 receptor is associated with low serum triglyceride levels.PMID 16278267Read ↗

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Melanocortin-4 receptor gene variant I103 is negatively associated with obesity.Semantic proximity Read ↗

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Association of the 103I <i>MC4R</i> allele with decreased body mass in 7937 participants of two population based surveysSemantic proximity Read ↗

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