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Article

Transcriptional profiling of androgen receptor (AR) mutants suggests instructive and permissive roles of AR signaling in germ cell development.

Molecular endocrinology (Baltimore, Md.) - 1 Apr 2007

Eacker Stephen M, Shima James E, Connolly Charles M, Sharma Manju, Holdcraft Robert W, Griswold Michael D, Braun Robert E

Abstract excerpt

The androgen receptor (AR) is a transcription factor that plays a critical role in male sexual development, spermatogenesis, and maintenance of hormonal homeostasis. Despite the extensive knowledge of the phenotypic consequences of mutations in Ar, very little is known about the transcriptional targets of AR within the testis. To identify potential targets of androgen signaling in the testis, we have analyzed the...

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Identifiers

PMID: 17244764
DOI: 10.1210/me.2006-0113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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