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Article

Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development.

International journal for parasitology - 1 Jun 2009

Lal Kalpana, Delves Michael J, Bromley Elizabeth, Wastling Jonathan M, Tomley Fiona M, Sinden Robert E

Abstract excerpt

Successful development of Plasmodium sexual stages is essential for parasite survival, but the genes involved are poorly understood. We 'knocked out' the male development gene-1 (mdv-1) locus in Plasmodium berghei and found it to be important in female gametocyte activation. Indirect immunofluorescence assays show MDV-1 has a punctate cytoplasmic distribution in gametocytes. After activation of both females and...

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PMID: 19136003
DOI: 10.1016/j.ijpara.2008.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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