Article
Interleukin-18 gene polymorphisms in Korean patients with Behçet's disease.
Clinical and experimental rheumatology - 1 Jan 2000
Jang W C, Park S B, Nam Y H, Lee S S, Kim J W, Chang I S, Kim K T, Chang H K
Abstract excerpt
OBJECTIVE: There is strong evidence that Th1-type cytokines play an important role in the pathogenesis of Behçet's disease (BD). Interleukin (IL)-18 is a proinflammatory cytokine that mediates Th1-polarized immune responses, and elevated levels of IL-18 have been observed in the sera and bronchoalveolar lavage fluid of patients with active BD. Therefore, the aim of this study was to investigate the potential...
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