Article
IL10 polymorphisms associated with Behçet's disease in Chinese Han.
Human immunology - 1 Mar 2014
Wu Ziyan, Zheng Wenjie, Xu Juanjuan, Sun Fei, Chen Hua, Li Ping, Chen Si, Shen Ming, Zhang Wen, You Xin, Wu Qingjun, Zhang Fengchun, Li Yongzhe
Abstract excerpt
OBJECTIVE: IL-10 is a potent anti-inflammatory cytokine that plays important roles in the pathogenesis of Behçet's disease (BD). Two genome-wide association studies have identified IL10 as a potential risk factor for BD. Here, we investigated the association between IL10 polymorphisms and BD in Chinese Han. METHODS: 407 BD patients and 679 healthy controls were enrolled, and genotyped by Sequenom MassArray system...
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