Article
CD11a, CD11c, and CD18 gene polymorphisms and susceptibility to Behçet's disease in Koreans.
Tissue antigens - 1 Oct 2014
Park S R, Park K S, Park Y J, Bang D, Lee E-S
Abstract excerpt
Lesions of Behçet's disease (BD) show vascular infiltrates of immune cells expressing integrins. β2 integrins (CD11/CD18) play a major role in cell migration to the inflammatory lesion and also induce cytokine production. Thus, genetic polymorphisms of CD11/CD18 may be associated with the pathogenesis of BD. In this study, nine single nucleotide polymorphisms (SNPs) of the CD11a, CD11c, and CD18 were genotyped...
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