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Article

Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families.

BMC cancer - 26 May 2008

Pylkäs Katri, Erkko Hannele, Nikkilä Jenni, Sólyom Szilvia, Winqvist Robert

Abstract excerpt

BACKGROUND: BRCA1 and BRCA2 are the two most important genes associated with familial breast and ovarian cancer susceptibility. In addition, PALB2 has recently been identified as a breast cancer susceptibility gene in several populations. Here we have evaluated whether large genomic rearrangement in these genes could explain some of Finnish breast and/or ovarian cancer families. METHODS: Altogether 61 index...

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Source

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Identifiers

PMID: 18501021
DOI: 10.1186/1471-2407-8-146
PMCID: PMC2413256

Genes

BRCA1
BRCA2
PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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