Article
eNOS genotype-dependent correlation between whole blood lead and plasma nitric oxide products concentrations.
Nitric oxide : biology and chemistry - 1 Feb 2006
Barbosa Fernando, Sandrim Valeria C, Uzuelli Juliana A, Gerlach Raquel F, Tanus-Santos Jose E
Abstract excerpt
Experimental data indicate that lead exposure decreases nitric oxide (NO) availability. However, no previous study has examined whether lead exposure affects plasma nitrite/nitrate (NO(x)) concentrations in humans. In addition, the T(-786)C polymorphism affects endothelial NO synthase (eNOS) expression and endogenous NO release. Here, we investigated whether there is an association between the circulating...
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