Article
T-786C polymorphism in endothelial NO synthase gene affects cerebral circulation in smokers: possible gene-environmental interaction.
Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2002
Nasreen Shampa, Nabika Toru, Shibata Hiroshi, Moriyama Hidehiko, Yamashita Kazuya, Masuda Junichi, Kobayashi Shotai
Abstract excerpt
Effects of smoking on white matter lesions, such as lacunar infarction and leukoaraiosis, are still controversial. We hypothesized that the endothelial NO synthase (eNOS) genotype was a modulating factor for the effect of smoking on cerebral circulation. We took a cross-sectional population from the participants of a health examination to study the effects of smoking and a single-nucleotide polymorphism in the...
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