Article
eNOS genotype is without effect on circulating nitrite/nitrate level in healthy male population.
Thrombosis research - 1 Jan 2005
Nagassaki Sabrina, Metzger Ingrid F, Souza-Costa Debora C, Marroni Aline S, Uzuelli Juliana A, Tanus-Santos Jose E
Abstract excerpt
INTRODUCTION: Nitric oxide (NO) plays an important role in the regulation of the cardiovascular system. It is produced by endothelial nitric oxide synthase (eNOS), which exhibits genetic polymorphisms. Although the clinically relevant polymorphism T(+IhI-786)C reduces eNOS-promoter activity, it is not clear whether circulating nitrite/nitrate (NOx) are affected by this polymorphism. MATERIALS AND METHODS: We...
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