Article
Centrosome amplification and multinuclear phenotypes are Induced by hydrogen peroxide.
Experimental & molecular medicine - 31 Oct 2005
Chae Sunyoung, Yun Chawon, Um Haeryun, Lee Jae Ho, Cho Hyeseong
Abstract excerpt
Multinucleated cells resulted from mitosis defect have been noted in pathophysiological states of the cells such as inflammation, senescence and cancer. Since oxidative stress has been known to correlate with these pathophysiological conditions, we tested the effect of H2O2 on the cell cycle prog...
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