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Article

Polymorphisms of the BRCA2 and RAD51 genes in breast cancer.

Breast cancer research and treatment - 1 Nov 2005

Sliwinski Tomasz, Krupa Renata, Majsterek Ireneusz, Rykala Jan, Kolacinska Agnieszka, Morawiec Zbigniew, Drzewoski Jozef, Zadrozny Marek, Blasiak Janusz

Abstract excerpt

We performed a case-control study (150 cases and 150 controls) to test the association between three polymorphisms in BRCA2 and RAD51 genes and breast cancer risk. Genotypes were determined in DNA from blood cells by PCR-RFLP. Cancer occurrence was strongly associated with the BRCA2 Met/1915Thr homozygous polymorphic variants, whereas heterozygous variant was associated with significant reduction in breast cancer...

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Source

Identifiers

PMID: 16261408
DOI: 10.1007/s10549-005-0672-5

Genes

BRCA2
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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