Article
Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach.
Lancet (London, England) - 1 Jan 2000
Brennan Paul, Hsu Charles C, Moullan Norman, Szeszenia-Dabrowska Neonilia, Lissowska Jolanta, Zaridze David, Rudnai Peter, Fabianova Eleonora, Mates Dana, Bencko Vladimir, Foretova Lenka, Janout Vladimir, Gemignani Federica, Chabrier Amelie, Hall Janet, Hung Rayjean J, Boffetta Paolo, Canzian Federico
Abstract excerpt
Whether consumption of cruciferous vegetables protects against lung cancer is unclear, largely because of potential confounding factors. We therefore studied the role of cruciferous vegetables in lung cancer after stratifying by GSTM1 and GSTT1 status, two genes implicated in the elimination of isothiocyanates, the likely chemopreventative compound. In 2141 cases and 2168 controls, weekly consumption of...
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