Establishment and characterization of "biphenotypic" acute leukemia cell lines with a variant Ph translocation t(9;22;10) (q34;q11;q22).

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Article

Establishment and characterization of "biphenotypic" acute leukemia cell lines with a variant Ph translocation t(9;22;10) (q34;q11;q22).

Human cell - 1 Mar 1998

Ariyasu T, Matsuo Y, Harashima A, Nakamura S, Takaba S, Tsubota T, Orita K

Abstract excerpt

We established two novel PH-positive acute leukemia cell lines with "biphenotypic" feature, NALM-27 and NALM-28, with t(9;22;10)(q34;q11;q22) from a patient with biphenotypic acute leukemia(BAL). The breakpoint cluster region (bcr) of the BCR gene was found to be rearranged in these cells by Sout...

Topics

Acute Disease
Adult
Cell Line
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 22
Chromosomes, Human, Pair 9
Fusion Proteins, bcr-abl
Humans
Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Male
Phenotype
Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Tumor Cells, Cultured

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Open in PubMed

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PMID: 9710720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9710720-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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