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Article

Targeting the glycans of gp120: a novel approach aimed at the Achilles heel of HIV.

The Lancet. Infectious diseases - 1 Nov 2005

Balzarini Jan

Abstract excerpt

The development of drug resistance in HIV compromises the long-term efficacy of current therapies. Furthermore, vaccine development faces huge problems, mainly because of the low antigenicity and immunogenicity of the HIV envelope glycoprotein gp120 and the efficient hiding of highly immunogenic epitopes by its glycans. There is evidence that mutant HIV strains containing glycosylation site deletions trigger the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 16253890
DOI: 10.1016/S1473-3099(05)70271-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Targeting the glycans of gp120: a novel approach aimed at the Achilles heel of HIV.PMID 16253890Read ↗

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Conservation, Compensation, and Evolution of N-Linked Glycans in the HIV-1 Group M Subtypes and Circulating Recombinant FormsSemantic proximity Read ↗

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