Article
Aberrant expression of human luteinizing hormone receptor by adrenocortical cells is sufficient to provoke both hyperplasia and Cushing's syndrome features.
The Journal of clinical endocrinology and metabolism - 1 Jan 2006
Mazzuco Tânia L, Chabre Olivier, Feige Jean-Jacques, Thomas Michaël
Abstract excerpt
CONTEXT: Aberrant expression of LH/human chorionic gonadotropin (hCG) receptor has been suggested in several cases of bilateral macronodular adrenal hyperplasia with Cushing's syndrome. The cortisol production is then directly controlled by endogenous secretion of LH/hCG. However, the direct invo...
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