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Article

Abnormal skin barrier in the etiopathogenesis of atopic dermatitis.

Current opinion in allergy and clinical immunology - 1 Oct 2009

Elias Peter M, Schmuth Matthias

Abstract excerpt

PURPOSE OF REVIEW: Many recent studies have revealed the key roles played by Th1/Th2 cell dysregulation, IgE production, mast cell hyperactivity, and dendritic cell signaling in the pathogenesis of atopic dermatitis. Accordingly, current therapy has been largely directed towards ameliorating Th2-mediated inflammation and/or pruritus. We will review here emerging evidence that the inflammation in atopic dermatitis...

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Identifiers

PMID: 19550302
DOI: 10.1097/ACI.0b013e32832e7d36
PMCID: PMC2852024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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