Article
Expression and functional analysis of genes deregulated in mouse placental overgrowth models: Car2 and Ncam1.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2005
Singh Umashankar, Sun Tong, Shi Wei, Schulz Ralph, Nuber Ulrike A, Varanou Aikaterini, Hemberger Myriam C, Elliott Rosemary W, Ohta Hiroshi, Wakayama Teruhiko, Fundele Reinald
Abstract excerpt
Different causes, such as maternal diabetes, cloning by nuclear transfer, interspecific hybridization, and deletion of some genes such as Esx1, Ipl, or Cdkn1c, may underlie placental overgrowth. In a previous study, we carried out comparative gene expression analysis in three models of placental hyperplasias, cloning, interspecies hybridization (IHPD), and Esx1 deletion. This study identified a large number of...
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