Article
Different molecular mechanisms underlie placental overgrowth phenotypes caused by interspecies hybridization, cloning, and Esx1 mutation.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 May 2004
Singh Umashankar, Fohn Laurel E, Wakayama Teruhiko, Ohgane Jun, Steinhoff Christine, Lipkowitz Bettina, Schulz Ralph, Orth Annie, Ropers H Hilger, Behringer Richard R, Tanaka Satoshi, Shiota Kunio, Yanagimachi Ryuzo, Nuber Ulrike A, Fundele Reinald
Abstract excerpt
To obtain a deeper insight into the genes and gene networks involved in the development of placentopathies, we have assessed global gene expression in three different models of placental hyperplasia caused by interspecies hybridization (IHPD), cloning by nuclear transfer, and mutation of the Esx1 gene, respectively. Comparison of gene expression profiles of approximately 13,000 expressed sequence tags (ESTs)...
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