Article
A prospective randomized study on the mobilization of CD34+ cells comparing continuous intravenous vs subcutaneous administration of rhG-CSF in normal donors.
Bone marrow transplantation - 1 Dec 2005
Lee K-E, Mun Y C, Nam S-H, Kwon J M, Lee S M, Lee M-A, Yoo E-S, Ahn J-Y, Kim J-H, Seong C-M
Abstract excerpt
The efficacy of mobilizing peripheral blood progenitor cells (PBPC) with continuous intravenous (c.i.v.) administration of rhG-CSF was randomly compared to subcutaneous (s.c.) administration, in 15 normal donors in each arm of the study for 6 days. The percentage and absolute numbers of CD34+ cells in the c.i.v. and s.c. groups increased maximally at day 3 and 5, respectively, when compared with the steady-state...
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