Article
Both early and committed haemopoietic progenitors are more frequent in peripheral blood than in bone marrow during mobilization induced by high-dose chemotherapy + G-CSF.
British journal of haematology - 1 Nov 1995
Tarella C, Benedetti G, Caracciolo D, Castellino C, Cherasco C, Bondesan P, Omedé P, Ruggieri D, Gianni A M, Pileri A
Abstract excerpt
Haemopoietic growth factor administration following high-dose chemotherapy markedly amplifies progenitor cell pool in the peripheral blood (PB). Collection and reinfusion of these cells enable rapid haemopoietic reconstitution following autograft. Less is known on engraftment potentiality of bone marrow (BM) cells taken under analogous conditions. To investigate this tissue, PB and BM were evaluated...
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