Article
Effect of glycosylation of recombinant human granulocytic colony-stimulating factor on expansion cultures of umbilical cord blood CD34+ cells.
Haematologica - 1 Jun 1999
Querol S, Cancelas J A, Amat L, Capmany G, Garcia J
Abstract excerpt
BACKGROUND AND OBJECTIVE: Granulocytic colony-stimulating factor (G-CSF) is a cytokine widely used for several purposes such as stem cell mobilization, treatment of neutropenia or in vitro cultures. Recombinant human G-CSF (rh-G-CSF) is available in two forms: a non-glycosylated (E. Coli-derived), and a glycosylated CHO-derived rhG-CSF. As previously shown, glycosylation gives a higher degree of homology between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.