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Article

Gene expression and DNA repair in progeroid syndromes and human aging.

Ageing research reviews - 1 Nov 2005

Kyng Kasper J, Bohr Vilhelm A

Abstract excerpt

Human progeroid syndromes are caused by mutations in single genes accelerating some but not all features of normal aging. Most progeroid disorders are linked to defects in genome maintenance, and while it remains unknown if similar processes underlie normal and premature aging, they provide useful models for the study of aging. Altered transcription is speculated to play a causative role in aging, and is involved...

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Identifiers

PMID: 16246641
DOI: 10.1016/j.arr.2005.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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