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Article

Wnt5 signaling in vertebrate pancreas development

24 Oct 2005

Abstract excerpt

BACKGROUND: Signaling by the Wnt family of secreted glycoproteins through their receptors, the frizzled (Fz) family of seven-pass transmembrane proteins, is critical for numerous cell fate and tissue polarity decisions during development. RESULTS: We report a novel role of Wnt signaling in organogenesis using the formation of the islet during pancreatic development as a model tissue. We used the advantages of the...

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Share to Developmental Biology and Gene Regulation
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Share to Wnt/β-catenin signaling in development and cancer

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PMID: 16246260
DOI: 10.1186/1741-7007-3-23

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