Article
Interleukin-6 genetic polymorphism and Chinese major depression.
Neuropsychobiology - 1 Jan 2005
Hong Chen-Jee, Yu Younger W-Y, Chen Tai-Jui, Tsai Shih-Jen
Abstract excerpt
BACKGROUND: It has been reported that serum concentrations of interleukin-6 (IL-6), a pro-inflammatory cytokine, were significantly higher in major depressive disorder (MDD). OBJECTIVES: The aim of the present study was to examine whether the IL-6 genetic variant confers susceptibility to MDD. METHODS: We genotyped a functional polymorphism in the promoter region (position -634) of the IL-6 gene in a sample of...
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