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Article

Genetic suppression analysis of non-antibiotic-producing mutants of the Streptomyces coelicolor absA locus.

Microbiology (Reading, England) - 1 Sept 1999

Anderson Todd, Brian Paul, Riggle Perry, Kong Renqiu, Champness Wendy

Abstract excerpt

The absA locus in Streptomyces coelicolor A3(2) was identified because mutations in it uncoupled sporulation from antibiotic synthesis: absA mutants failed to produce any of the four antibiotics characteristic of S. coelicolor. These mutants are now shown to contain point mutations in the absA1 gene which encodes the histidine kinase sensor-transmitter protein of a two-component signalling system. The absA1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10517587
DOI: 10.1099/00221287-145-9-2343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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