Article
Gearing up for genome-wide gene-association studies.
Human molecular genetics - 15 Oct 2005
Farrall Martin, Morris Andrew P
Abstract excerpt
One of the grand challenges of human genetics to systematically map by gene-association susceptibility genes for complex diseases is underway. High-throughput genotyping platforms have been developed; a comprehensive map of human genetic variation (HapMap) to guide efficient marker selection is imminent and many researchers have assembled suitable cohorts of patients. Expectations are understandably high and it...
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