Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular evolution of the sheep prion protein gene.

Proceedings. Biological sciences - 22 Nov 2005

Slate Jon

Abstract excerpt

Transmissible spongiform encephalopathies (TSEs) are infectious, fatal neurodegenerative diseases characterized by aggregates of modified forms of the prion protein (PrP) in the central nervous system. Well known examples include variant Creutzfeldt-Jakob Disease (vCJD) in humans, BSE in cattle, chronic wasting disease in deer and scrapie in sheep and goats. In humans, sheep and deer, disease susceptibility is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to PrPC Proteins
Share to Ruminants
Share to Selection, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to United Kingdom

Share to United States

Share to Evolution, Molecular

Share to Phylogeny

Source

Open in PubMed Open full text

Identifiers

PMID: 16243700
DOI: 10.1098/rspb.2005.3259
PMCID: PMC1559970

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular evolution of the sheep prion protein gene.PMID 16243700Read ↗

PrP genetics in ruminant transmissible spongiform encephalopathies.Semantic proximity Read ↗

Genotype-dependent molecular evolution of sheep bovine spongiform encephalopathy (BSE) prions in vitro affects their zoonotic potential.Semantic proximity Read ↗

Selective Breeding for Disease Resistant PRNP Variants to Manage Chronic Wasting Disease in Farmed Whitetail DeerSemantic proximity Read ↗

Excessive replacement changes drive evolution of global sheep prion protein (PRNP) sequences.Semantic proximity Read ↗

[Research progress on genetic diversity of sheep PRNP and resistance breeding].Semantic proximity Read ↗

Prion gene sequence variation within diverse groups of U.S. sheep, beef cattle, and deer.Semantic proximity Read ↗

The role of genetics in chronic wasting disease of North American cervids.Semantic proximity Read ↗

Selective Breeding for Disease-Resistant PRNP Variants to Manage Chronic Wasting Disease in Farmed Whitetail Deer.Semantic proximity Read ↗

Enhanced virulence of sheep-passaged bovine spongiform encephalopathy agent is revealed by decreased polymorphism barriers in prion protein conversion studies.Semantic proximity Read ↗

Prion protein gene (PRNP) variants and evidence for strong purifying selection in functionally important regions of bovine exon 3.Semantic proximity Read ↗

Prion diseases: BSE in sheep bred for resistance to infection.Semantic proximity Read ↗

Eradication of scrapie in a Massese sheep flock by PrP allele selection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.