Article
Characterisation of a human glioblastoma cell line (LI) expressing hypothalamic and pituitary hormones.
Experimental brain research - 1 Jan 1992
Savarese A, Annicchiarico-Petruzzelli M, Citro G, Zupi G, Spagnoli L G, Colantoni A, Vernole P, Stephanou A, Knight R A, Guerrieri P
Abstract excerpt
The human glioblastoma cell line LI showed morphological features typical of its neuroectodermal origin. Cells were positive by immunofluorescence to GFAP, MHC class II, and L1 determinants. Cytogenetic analysis showed the presence of a modal chromosome number of 63, ranging from 58 to 69 chromos...
Topics
- Blotting, Northern
- Cytogenetics
- DNA, Neoplasm
- Glioma
- Growth Hormone-Releasing Hormone
- Hormones
- Humans
- Hypothalamus
- Insulin-Like Growth Factor II
- Male
- Microscopy, Electron
- Middle Aged
- Nervous System Neoplasms
- Phenotype
- Pituitary Hormones