Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterisation of a human glioblastoma cell line (LI) expressing hypothalamic and pituitary hormones.

Experimental brain research - 1 Jan 1992

Savarese A, Annicchiarico-Petruzzelli M, Citro G, Zupi G, Spagnoli L G, Colantoni A, Vernole P, Stephanou A, Knight R A, Guerrieri P

Abstract excerpt

The human glioblastoma cell line LI showed morphological features typical of its neuroectodermal origin. Cells were positive by immunofluorescence to GFAP, MHC class II, and L1 determinants. Cytogenetic analysis showed the presence of a modal chromosome number of 63, ranging from 58 to 69 chromosomes (DNA index was 1.6). Northern blot analysis demonstrated the presence of mRNA transcripts specific for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glioma

Share to Insulin-Like Growth Factor II

Share to Microscopy, Electron

Share to Phenotype

Share to Tretinoin

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 1623982
DOI: 10.1007/BF00228256

Genes

GHRH
POMC
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Characterisation of a human glioblastoma cell line (LI) expressing hypothalamic and pituitary hormones.PMID 1623982Read ↗

Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes.Semantic proximity Read ↗

Interleukin-13 sensitivity and receptor phenotypes of human glial cell lines: non-neoplastic glia and low-grade astrocytoma differ from malignant glioma.Semantic proximity Read ↗

Growth hormone and insulin-like growth factor-I: effects on the growth of glioma cell lines.Semantic proximity Read ↗

Identification and characterization of a novel member of the fibroblast growth factor family.Semantic proximity Read ↗

Molecular biology and biochemistry of brain tumoursSemantic proximity Read ↗

The expression of the pituitary growth hormone-releasing hormone receptor and its splice variants in normal and neoplastic human tissuesSemantic proximity Read ↗

PKA and PKC activation induces opposite glial fibrillary acidic protein (GFAP) expression and morphology changes in a glioblastoma multiform cell line of clonal origin.Semantic proximity Read ↗

The IGF/IGFBP system in CNS malignancySemantic proximity Read ↗

Changes in glial fibrillary acidic protein and karyotype during culturing of two cell lines established from human glioblastoma multiformeSemantic proximity Read ↗

Retinoids Inhibit Human Glioma Cell Proliferation and Migration in Primary Cell Cultures But Not in Established Cell LinesSemantic proximity Read ↗

Morphological heterogeneity and phenotype modifications during long term in vitro cultures of six new human glioblastoma cell lines.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.