Article
Morphological heterogeneity and phenotype modifications during long term in vitro cultures of six new human glioblastoma cell lines.
Tumori - 30 Apr 1990
Dipasquale B, Colombatti M, Tridente G
Abstract excerpt
Long term in vitro cultures of six human malignant gliomas were established to obtain permanent lines and to assess, under conditions of prolonged culture, changes in morphology and phenotype of neoplastic cells and the extent of these modifications. We analyzed expression of the following markers by immunocytochemistry: glioma-specific antigens (GE2 and CG12), fibronectin, intermediate filaments (GFAP, vimentin,...
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