Article
A genome-wide sequence-independent comparative analysis of insertion-deletion polymorphisms in multiple Mycobacterium tuberculosis strains.
Research in microbiology - 1 Apr 2006
Azhikina Tatyana, Gvozdevsky Nikolay, Botvinnik Anna, Fushan Alexey, Shemyakin Igor, Stepanshina Valentina, Lipin Mikhail, Barry Clifton, Sverdlov Eugene
Abstract excerpt
We applied an enhanced version of subtractive hybridization for comparative analyses of indel differences between genomes of several Mycobacterium tuberculosis strains widespread in Russian regions, and the H37Rv reference strain. A number of differences were detected and partially analyzed, thus demonstrating the practicality of the approach. A majority of the insertions found were shared by all Russian strains,...
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