Article
Comparative analysis of bacterial genomes: identification of divergent regions in mycobacterial strains using an anchor-based approach.
Nucleic acids research - 1 Jan 2007
Vishnoi Anchal, Roy Rahul, Bhattacharya Alok
Abstract excerpt
Comparative genomic approaches are useful in identifying molecular differences between organisms. Currently available methods fail to identify small changes in genomes, such as expansion of short repetitive motifs and to analyse divergent sequences. In this report, we describe an anchor-based whole genome comparison (ABWGC) method. ABWGC is based on random sampling of anchor sequences from one genome, followed by...
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