Article
Ligand and loop variations at type 1 copper sites: influence on structure and reactivity.
Dalton transactions (Cambridge, England : 2003) - 7 Nov 2005
Dennison Christopher
Abstract excerpt
Type 1 (T1) copper sites promote biological electron transfer and are found in the cupredoxins and a number of copper-containing enzymes including the multi-copper oxidases. A T1 copper site usually has a distorted tetrahedral geometry with strong ligands provided by the thiolate sulfur of a Cys and the imidazole nitrogens of two His residues. The active site structure is typically completed by a weak axial Met...
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