Article
Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide.
The American journal of psychiatry - 1 Sept 1999
Turecki G, Brière R, Dewar K, Antonetti T, Lesage A D, Séguin M, Chawky N, Vanier C, Alda M, Joober R, Benkelfat C, Rouleau G A
Abstract excerpt
OBJECTIVE: Postmortem studies have indicated that suicide victims have greater serotonin receptor 2A (5-HTR2A) binding in prefrontal brain regions. However, there remains some controversy regarding the biological specificity of these findings. The authors hypothesized that the variance observed in brain 5-HTR2A binding is genetically mediated, at least in part. METHOD: Postmortem data from 56 subjects who had...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.