Article
Lack of association between serotonin 5-HT1B receptor gene polymorphism and suicidal behavior.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2003
Rujescu Dan, Giegling Ina, Sato Tetsuya, Möller Hans-Jürgen
Abstract excerpt
A genetic susceptibility to suicide attempts has been repeatedly suggested by family-, twin-, and adoption-studies. Because elevated impulsive aggression is one of the most prominent characteristics of suicide attempters and aggressive behavior has been reported in 5-HT1B receptor gene knockout mice, the serotonin receptor 1B gene (5-HT1B) is an attractive candidate. The distribution of a polymorphism (G861C) in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
