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Article

Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer.

The Journal of biological chemistry - 30 Dec 2005

Gokhale Nikhil A, Abraham Alexandra, Digman Michelle A, Gratton Enrico, Cho Wonhwa

Abstract excerpt

Annexin A2 is a phospholipid-binding protein that forms a heterotetramer (annexin II-p11 heterotetramer; A2t) with p11 (S100A10). It has been reported that annexin A2 is involved in binding to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and in inducing membrane microdomain formation. To understand the mechanisms underlying these findings, we determined the membrane binding properties of annexin A2 wild...

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Identifiers

PMID: 16230353
DOI: 10.1074/jbc.M508129200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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