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Human embryonic stem cell genes <i>OCT4, NANOG, STELLAR</i>, and <i>GDF3</i> are expressed in both seminoma and breast carcinoma

14 Oct 2005

Abstract excerpt

BACKGROUND: The seminoma class of testicular germ cell tumor (TGCT) are characterized by a morphological resemblance to primordial germ cells (PGCs) or gonocytes, and chromosome duplications at 12p. Recently, it was determined that human embryonic stem cells (hESCs) express genes in common with PGCs, and that three of these genes, GDF3, STELLAR, and NANOG, are located on 12p. The current study was designed to...

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PMID: 16228988
DOI: 10.1002/cncr.21432

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Human embryonic stem cell genes <i>OCT4, NANOG, STELLAR</i>, and <i>GDF3</i> are expressed in both seminoma and breast carcinomaPMID 16228988Read ↗

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