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NANOG controls testicular germ cell tumour stemness through regulation of MIR9-2

1 May 2024

Abstract excerpt

BACKGROUND: Testicular germ cell tumours (TGCTs) represent a clinical challenge; they are most prevalent in young individuals and are triggered by molecular mechanisms that are not fully understood. The origin of TGCTs can be traced back to primordial germ cells that fail to mature during embryonic development. These cells express high levels of pluripotency factors, including the transcription factor NANOG which...

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PMID: 38693576
DOI: 10.1186/s13287-024-03724-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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