Analysis of constructed E gene mutants of mouse hepatitis virus confirms a pivotal role for E protein in coronavirus assembly.

doi:10.1128/JVI.72.10.7885-7894.1998

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Article

Analysis of constructed E gene mutants of mouse hepatitis virus confirms a pivotal role for E protein in coronavirus assembly.

Journal of virology - 1 Oct 1998

Fischer F, Stegen C F, Masters P S, Samsonoff W A

Abstract excerpt

Expression studies have shown that the coronavirus small envelope protein E and the much more abundant membrane glycoprotein M are both necessary and sufficient for the assembly of virus-like particles in cells. As a step toward understanding the function of the mouse hepatitis virus (MHV) E prot...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
DNA, Viral
Mice
Microscopy, Electron
Molecular Sequence Data
Murine hepatitis virus
Mutagenesis
Mutation
Phenotype
Sequence Homology, Amino Acid
Virus Assembly

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