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Article

Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum.

Trends in genetics : TIG - 1 Dec 2005

Dermaut Bart, Kumar-Singh Samir, Rademakers Rosa, Theuns Jessie, Cruts Marc, Van Broeckhoven Christine

Abstract excerpt

In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease. Here, we focus on recent genotype-phenotype correlative studies in presenile AD and the frontotemporal dementia (FTD) complex of disorders. Together, these studies...

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Identifiers

PMID: 16221505
DOI: 10.1016/j.tig.2005.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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