Article
Frontotemporal dementia genetics.
Journal of geriatric psychiatry and neurology - 1 Jan 1998
Wilhelmsen K C
Abstract excerpt
Frontotemporal dementia (FTD) is the most common syndrome in which the focus of neurodegeneration is the frontal lobes. FTD is frequently familial. It is also often due to a susceptibility locus on chromosome 17q21-22. Some 17q21-22-linked families have mutations in the tau gene and most have mic...
Topics
- Aged
- Amino Acid Sequence
- Chromosomes, Human, Pair 17
- DNA Mutational Analysis
- Dementia
- Frontal Lobe
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Molecular Sequence Data
- Nerve Degeneration
- Temporal Lobe
- tau Proteins