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Article

Genetic variance of SGK-1 is associated with blood pressure, blood pressure change over time and strength of the insulin-diastolic blood pressure relationship.

Kidney international - 1 Nov 2005

von Wowern Fredrik, Berglund Göran, Carlson Joyce, Månsson Henrik, Hedblad Bo, Melander Olle

Abstract excerpt

BACKGROUND: Insulin stimulation of the serum- and glucocorticoid-regulated kinase 1 (SGK-1) prolongs the half-life of the epithelial sodium channel, a protein which is essential for blood pressure regulation. The aim of this study was to investigate if variation in the SGK-1 gene is associated with increased blood pressure and strength of the insulin-blood pressure relationship. METHODS: A promoter C/T, an intron...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 16221215
DOI: 10.1111/j.1523-1755.2005.00672.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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