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Article

Rapid and accurate determination of MYCN copy number and 1p deletion in neuroblastoma by quantitative PCR.

Pediatric blood & cancer - 1 Jun 2006

Anderson John, Gibson Sian, Williamson Dan, Rampling Dyanne, Austin Catherine, Shipley Janet, Sebire Neil, Brock Penelope

Abstract excerpt

MYCN amplification and 1p36 deletion are adverse prognostic factors in neuroblastoma, and rapid accurate determination of MYCN amplification is essential for risk stratification. MYCN copy number and 1p36 deletion status were determined by fluorescence in situ hybridization (FISH) and real time PCR in a diagnostic pathology laboratory setting on 35 consecutive patients with neuroblastoma. The PCR technique was...

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Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, myc

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Share to In Situ Hybridization, Fluorescence

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Source

Identifiers

PMID: 16220551
DOI: 10.1002/pbc.20311

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Rapid and accurate determination of MYCN copy number and 1p deletion in neuroblastoma by quantitative PCR.PMID 16220551Read ↗

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The performance of semi-quantitative differential PCR is similar to that of real-time PCR for the detection of the MYCN gene in neuroblastomasSemantic proximity Read ↗

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Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in NeuroblastomaSemantic proximity Read ↗

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MYCN amplification plus 1p36 loss of heterozygosity predicts ultra high risk in bone marrow metastatic neuroblastomaSemantic proximity Read ↗

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