Article
The Drosophila tweety family: molecular candidates for large-conductance Ca2+-activated Cl- channels.
Experimental physiology - 1 Jan 2006
Suzuki Makoto
Abstract excerpt
Calcium-activated chloride currents (I(Cl(Ca))) can be recorded in almost all cells, but the molecular identity of the channels underlying this Cl- conductance is still incompletely understood. Here, I report that tweety, a gene located in Drosophila flightless, possesses five or six transmembrane segments, and that a human homologue of tweety (hTTYH3) is a novel large-conductance Ca2+-activated Cl- channel,...
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