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Article

A novel human Cl(-) channel family related to Drosophila flightless locus.

The Journal of biological chemistry - 21 May 2004

Suzuki Makoto, Mizuno Atsuko

Abstract excerpt

Large conductance chloride (maxi-Cl(-)) currents have been recorded in some cells, but there is still little information on the molecular nature of the channel underlying this conductance. We report here that tweety, a gene located in Drosophila flightless, has a structure similar to those of known channels and that human homologues of tweety (hTTYH1-3) are novel maxi-Cl(-) channels. hTTYH3 mRNA was found to be...

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Identifiers

PMID: 15010458
DOI: 10.1074/jbc.M313813200

Genes

TTYH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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