Article
Developmental and reproductive performance in circadian mutant mice.
Human reproduction (Oxford, England) - 1 Jan 2006
Dolatshad H, Campbell E A, O'Hara L, Maywood E S, Hastings M H, Johnson M H
Abstract excerpt
BACKGROUND: Genes underlying circadian rhythm generation are expressed in many tissues. We explore a role for circadian rhythms in the timing and efficacy of mouse reproduction and development using a genetic approach. METHODS: We compare fecundity in Clock(Delta19) mutant mice (a dominant-negative protein essential for circadian rhythm activity) and in Vipr2-/- null mutant mice (affecting the generation and...
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